TestGene

     Reagents kit for fetal Rh factor using maternal blood since 10th week of pregnangcy. Is used for RhD negative pregnant women to prevent Rh incompatibility.

Reagents kits are intended for fetal Rh factor gene identification in blood of rhesus-negative pregnant woman by polymerase chain reaction (PCR) with hybridization-fluorescent detection. DNA probes isolated from blood plasma are the material for PCR. 

Application for the kit - non invasive laboratory diagnostic for fetal RH factor. Also the kit can be used for detection of minimal concentration of RHD gene in other biological fluids. The kit is intended for use medical and healthcare institutions including diagnostic and crimialistic laboratory as well as for scientific purpose.

15% of pregnant women are rhesus-negative therefore development of rhesus incompatibility, one of the most frequent reasons of hemolytic disease of fetus and newborns, is possible in 50% of cases. Hemolytic disease of fetus and newborns is the most frequent reason of intrauterine fetal death and infant mortality. As of today the single method of fetal rhesus-factor determination is the test of material obtained by invasive way (chorion biopsy or cordocentesis).